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Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim
The BH3-only class of Bcl-2 family proteins triggers mitochondrial apoptosis. Several mechanisms are used to restrain the pro-apoptotic activity of these proteins. Dynein light chain (DYNLL) 1 and 2 has been proposed to negatively regulate the activity of Bim and Bmf, respectively, and the Bim–DYNLL...
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| Опубликовано в: : | Cell Death Differ |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206095/ https://ncbi.nlm.nih.gov/pubmed/31189926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0365-y |
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