Cargando...
The deubiquitinase Usp27x stabilizes the BH3‐only protein Bim and enhances apoptosis
Bim is a pro‐apoptotic Bcl‐2 family member of the BH3‐only protein subgroup. Expression levels of Bim determine apoptosis susceptibility in non‐malignant and in tumour cells. Bim protein expression is downregulated by proteasomal degradation following ERK‐dependent phosphorylation and ubiquitination...
Gardado en:
| Publicado en: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341510/ https://ncbi.nlm.nih.gov/pubmed/27013495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541392 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|