लोड हो रहा है...
The deubiquitinase Usp27x stabilizes the BH3‐only protein Bim and enhances apoptosis
Bim is a pro‐apoptotic Bcl‐2 family member of the BH3‐only protein subgroup. Expression levels of Bim determine apoptosis susceptibility in non‐malignant and in tumour cells. Bim protein expression is downregulated by proteasomal degradation following ERK‐dependent phosphorylation and ubiquitination...
में बचाया:
| में प्रकाशित: | EMBO Rep |
|---|---|
| मुख्य लेखकों: | , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
John Wiley and Sons Inc.
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341510/ https://ncbi.nlm.nih.gov/pubmed/27013495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201541392 |
| टैग : |
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