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Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells

Emerging evidence indicates that mesenchymal stromal cells (MSCs) have an important role in cancer metastasis. Although tumor microenvironment, which includes MSCs and immune cells, can be altered by ionizing radiation (IR), whether irradiation can promote metastasis through MSCs remains unclear. Us...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Zheng, Zhiyuan, Jia, Shanfen, Shao, Changshun, Shi, Yufang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206094/
https://ncbi.nlm.nih.gov/pubmed/32382015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2546-5
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