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Model of vaccine efficacy against HSV-2 superinfection of HSV-1 seropositive mice demonstrates protection by antibodies mediating cellular cytotoxicity

A majority of the world’s population is infected with HSV-1, highlighting the need for vaccines that are effective in HSV-1-seropositive hosts. We established a superinfection model by infecting mice intranasally with a sublethal dose of HSV-1, which results in high rates of seropositive, latently i...

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Bibliografiska uppgifter
I publikationen:NPJ Vaccines
Huvudupphovsmän: Burn Aschner, Clare, Knipe, David M., Herold, Betsy C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206093/
https://ncbi.nlm.nih.gov/pubmed/32411398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-0184-7
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