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Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain
Age-related phenotypic changes of cerebromicrovascular endothelial cells lead to dysregulation of cerebral blood flow and blood-brain barrier disruption, promoting the pathogenesis of vascular cognitive impairment (VCI). In recent years, endothelial cell senescence has emerged as a potential mechani...
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| Veröffentlicht in: | GeroScience |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer International Publishing
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205992/ https://ncbi.nlm.nih.gov/pubmed/32236824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00177-1 |
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