Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain

Age-related phenotypic changes of cerebromicrovascular endothelial cells lead to dysregulation of cerebral blood flow and blood-brain barrier disruption, promoting the pathogenesis of vascular cognitive impairment (VCI). In recent years, endothelial cell senescence has emerged as a potential mechani...

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Vydáno v:GeroScience
Hlavní autoři: Kiss, Tamas, Nyúl-Tóth, Ádám, Balasubramanian, Priya, Tarantini, Stefano, Ahire, Chetan, DelFavero, Jordan, Yabluchanskiy, Andriy, Csipo, Tamas, Farkas, Eszter, Wiley, Graham, Garman, Lori, Csiszar, Anna, Ungvari, Zoltan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205992/
https://ncbi.nlm.nih.gov/pubmed/32236824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00177-1
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