Mitochondrial base excision repair positively correlates with longevity in the liver and heart of mammals

Damage to DNA is especially important for aging. High DNA repair could contribute, in principle, to lower such damage in long-lived species. However, previous studies showed that repair of endogenous damage to nuclear DNA (base excision repair, BER) is negatively or not correlated with mammalian lon...

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Udgivet i:GeroScience
Main Authors: Gredilla, Ricardo, Sánchez-Román, Inés, Gómez, Alexia, López-Torres, Mónica, Barja, Gustavo
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205949/
https://ncbi.nlm.nih.gov/pubmed/31970600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00158-4
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