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Mitochondrial DNA repair and association with aging - an update
Mitochondrial DNA is constantly exposed to oxidative injury. Due to its location close to the main site of reactive oxygen species, the inner mitochondrial membrane, mtDNA is more susceptible than nuclear DNA to oxidative damage. The accumulation of DNA damage is thought to play a critical role in t...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879476/ https://ncbi.nlm.nih.gov/pubmed/20096766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2010.01.017 |
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