Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis

In type 1 diabetes (T1D), autoimmune destruction of pancreatic β cells leads to insulin deficiency and loss of glycemic control. However, knowledge about human pancreas pathophysiology in T1D remains incomplete. To address this limitation, we established a pancreas tissue slice platform of donor org...

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Publicat a:JCI Insight
Autors principals: Panzer, Julia K., Hiller, Helmut, Cohrs, Christian M., Almaça, Joana, Enos, Stephen J., Beery, Maria, Cechin, Sirlene, Drotar, Denise M., Weitz, John R., Santini, Jorge, Huber, Mollie K., Muhammad Fahd Qadir, Mirza, Pastori, Ricardo L., Domínguez-Bendala, Juan, Phelps, Edward A., Atkinson, Mark A., Pugliese, Alberto, Caicedo, Alejandro, Kusmartseva, Irina, Speier, Stephan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Technical Advance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205437/
https://ncbi.nlm.nih.gov/pubmed/32324170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134525
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