Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis

In type 1 diabetes (T1D), autoimmune destruction of pancreatic β cells leads to insulin deficiency and loss of glycemic control. However, knowledge about human pancreas pathophysiology in T1D remains incomplete. To address this limitation, we established a pancreas tissue slice platform of donor org...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Panzer, Julia K., Hiller, Helmut, Cohrs, Christian M., Almaça, Joana, Enos, Stephen J., Beery, Maria, Cechin, Sirlene, Drotar, Denise M., Weitz, John R., Santini, Jorge, Huber, Mollie K., Muhammad Fahd Qadir, Mirza, Pastori, Ricardo L., Domínguez-Bendala, Juan, Phelps, Edward A., Atkinson, Mark A., Pugliese, Alberto, Caicedo, Alejandro, Kusmartseva, Irina, Speier, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205437/
https://ncbi.nlm.nih.gov/pubmed/32324170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134525
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