S100B single nucleotide polymorphisms exhibit sex-specific associations with chronic pain in sickle cell disease in a largely African-American cohort

BACKGROUND: Pain in sickle cell disease (SCD) is severe and multifaceted resulting in significant differences in its frequency and intensity among individuals. In this study, we examined the influence of S100B gene single nucleotide polymorphisms (SNP) on acute and chronic pain variability in SCD. M...

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Veröffentlicht in:PLoS One
Hauptverfasser: Jhun, Ellie H., Sadhu, Nilanjana, He, Ying, Yao, Yingwei, Wilkie, Diana J., Molokie, Robert E., Wang, Zaijie Jim
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205279/
https://ncbi.nlm.nih.gov/pubmed/32379790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232721
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