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S100B single nucleotide polymorphisms exhibit sex-specific associations with chronic pain in sickle cell disease in a largely African-American cohort

BACKGROUND: Pain in sickle cell disease (SCD) is severe and multifaceted resulting in significant differences in its frequency and intensity among individuals. In this study, we examined the influence of S100B gene single nucleotide polymorphisms (SNP) on acute and chronic pain variability in SCD. M...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jhun, Ellie H., Sadhu, Nilanjana, He, Ying, Yao, Yingwei, Wilkie, Diana J., Molokie, Robert E., Wang, Zaijie Jim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205279/
https://ncbi.nlm.nih.gov/pubmed/32379790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232721
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