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Glucocorticoid receptor single nucleotide polymorphisms are associated with acute crisis pain in sickle cell disease

AIM: Pain in sickle cell disease patients is heterogeneous and genetic polymorphisms may predispose an individual to varied vulnerability to painful events. We studied the association of SNPs in the glucocorticoid receptor gene (NR3C1) with pain in sickle cell disease. METHOD: Acute pain was scored...

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Bibliografski detalji
Izdano u:Pharmacogenomics
Glavni autori: Jhun, Ellie H, Sadhu, Nilanjana, Yao, Yingwei, He, Ying, Molokie, Robert E, Wilkie, Diana J, Wang, Zaijie Jim
Format: Artigo
Jezik:Inglês
Izdano: Future Medicine Ltd 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275559/
https://ncbi.nlm.nih.gov/pubmed/30079801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2018-0064
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