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Phenylethanolamine N-methyltransferase gene polymorphisms associate with crisis pain in sickle cell disease patients

AIM: Phenylethanolamine N-methyltransferase (PNMT) catalyzes the conversion of sympathetic neurotransmitter norepinephrine to epinephrine. We examined the association of PNMT polymorphisms with acute and chronic pain in sickle cell disease (SCD). METHODS: Utilization of emergency care owing to painf...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Sadhu, Nilanjana, Jhun, Ellie H, Posen, Andrew, Yao, Yingwei, He, Ying, Molokie, Robert E, Wilkie, Diana J, Wang, Zaijie J
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202258/
https://ncbi.nlm.nih.gov/pubmed/32162598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2019-0096
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