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Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease
The role of the renal organic anion transporters OAT1 (also known as SLC22A6, originally identified as NKT) and OAT3 (also known as SLC22A8) in chronic kidney disease (CKD) remains poorly understood. This is particularly so from the viewpoint of residual proximal tubular secretion, a key adaptive me...
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| Publié dans: | JCI Insight |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205256/ https://ncbi.nlm.nih.gov/pubmed/32271169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133817 |
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