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Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters

The proximal tubule of the kidney plays a crucial role in the renal handling of drugs (e.g., diuretics), uremic toxins (e.g., indoxyl sulfate), environmental toxins (e.g., mercury, aristolochic acid), metabolites (e.g., uric acid), dietary compounds, and signaling molecules. This process is dependen...

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Detalhes bibliográficos
Publicado no:Clin J Am Soc Nephrol
Main Authors: Nigam, Sanjay K., Wu, Wei, Bush, Kevin T., Hoenig, Melanie P., Blantz, Roland C., Bhatnagar, Vibha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633783/
https://ncbi.nlm.nih.gov/pubmed/26490509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.02440314
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