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Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes

In vitro data indicates that the kidney proximal tubule (PT) transporters of uremic toxins and solutes (e.g., indoxyl sulfate, p-cresol sulfate, kynurenine, creatinine, urate) include two “drug” transporters of the organic anion transporter (OAT) family: OAT1 (SLC22A6, originally NKT) and OAT3 (SLC2...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Wu, Wei, Bush, Kevin T., Nigam, Sanjay K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504054/
https://ncbi.nlm.nih.gov/pubmed/28694431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04949-2
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