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Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors

The multispecific organic anion drug transporters OAT6 (SLC22A20) and OAT1 (SLC22A6) are expressed in nasal epithelial cells and both can bind odorants. Sequence analysis of OAT6 revealed an evolutionarily conserved 79-amino acid (AA) fragment present not only in OAT6 but also in other SLC22 transpo...

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Détails bibliographiques
Publié dans:Drug Metab Dispos
Auteurs principaux: Wu, Wei, Bush, Kevin T., Liu, Henry C., Zhu, Christopher, Abagyan, Ruben, Nigam, Sanjay K.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658493/
https://ncbi.nlm.nih.gov/pubmed/26358290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.065250
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