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Crystal structure of the mitochondrial protein mitoNEET bound to a benze-sulfonide ligand
MitoNEET (gene cisd1) is a mitochondrial outer membrane [2Fe-2S] protein and is a potential drug target in several metabolic diseases. Previous studies have demonstrated that mitoNEET functions as a redox-active and pH-sensing protein that regulates mitochondrial metabolism, although the structural...
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| Pubblicato in: | Commun Chem |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205193/ https://ncbi.nlm.nih.gov/pubmed/32382661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42004-019-0172-x |
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