Crystal structure of the mitochondrial protein mitoNEET bound to a benze-sulfonide ligand

MitoNEET (gene cisd1) is a mitochondrial outer membrane [2Fe-2S] protein and is a potential drug target in several metabolic diseases. Previous studies have demonstrated that mitoNEET functions as a redox-active and pH-sensing protein that regulates mitochondrial metabolism, although the structural...

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Udgivet i:Commun Chem
Main Authors: Geldenhuys, Werner J., Long, Timothy E., Saralkar, Pushkar, Iwasaki, Toshio, Nuñez, Raisa A.A., Nair, Rajesh R., Konkle, Mary E., Menze, Michael A., Pinti, Mark V., Hollander, John M., Hazlehurst, Lori A., Robart, Aaron R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205193/
https://ncbi.nlm.nih.gov/pubmed/32382661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42004-019-0172-x
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