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The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication
The tumour suppressor breast cancer type 1 susceptibility protein (BRCA1) promotes DNA double-strand break (DSB) repair by homologous recombination and protects DNA replication forks from attrition. BRCA1 partners with BRCA1-associated RING domain protein 1 (BARD1) and other tumour suppressor protei...
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Udgivet i: | Nat Rev Mol Cell Biol |
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Main Authors: | , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
2020
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7204409/ https://ncbi.nlm.nih.gov/pubmed/32094664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-020-0218-z |
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