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The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

The tumour suppressor breast cancer type 1 susceptibility protein (BRCA1) promotes DNA double-strand break (DSB) repair by homologous recombination and protects DNA replication forks from attrition. BRCA1 partners with BRCA1-associated RING domain protein 1 (BARD1) and other tumour suppressor protei...

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Bibliografiske detaljer
Udgivet i:Nat Rev Mol Cell Biol
Main Authors: Tarsounas, Madalena, Sung, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204409/
https://ncbi.nlm.nih.gov/pubmed/32094664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-020-0218-z
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