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Wdr-1- is Essential for F-actin Interaction with Focal Adhesions in Platelets
OBJECTIVE: Wdr-1, an actin interacting protein, enhances cofilin’s capacity to accelerate depolymerization of F-actin filaments. Wdr-1-deficient mice have impaired hemostasis due to defective inside-out integrin signaling in platelets. Here, we studied the role of Wdr-1 on outside-in signaling neces...
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| Pubblicato in: | Blood Coagul Fibrinolysis |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7204405/ https://ncbi.nlm.nih.gov/pubmed/29995657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000756 |
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