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Wdr-1- is Essential for F-actin Interaction with Focal Adhesions in Platelets

OBJECTIVE: Wdr-1, an actin interacting protein, enhances cofilin’s capacity to accelerate depolymerization of F-actin filaments. Wdr-1-deficient mice have impaired hemostasis due to defective inside-out integrin signaling in platelets. Here, we studied the role of Wdr-1 on outside-in signaling neces...

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書誌詳細
出版年:Blood Coagul Fibrinolysis
主要な著者: Dasgupta, Swapan K., Thiagarajan, Perumal
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204405/
https://ncbi.nlm.nih.gov/pubmed/29995657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MBC.0000000000000756
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