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Comprehensive dissection of dispensable genomic regions in Streptomyces based on comparative analysis approach

BACKGROUND: Large-scale genome reduction has been performed to significantly improve the performance of microbial chassis. Identification of the essential or dispensable genes is pivotal for genome reduction to avoid synthetic lethality. Here, taking Streptomyces as an example, we developed a combin...

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書誌詳細
出版年:Microb Cell Fact
主要な著者: Bu, Qing-Ting, Li, Yue-Ping, Xie, Huang, Wang, Jue, Li, Zi-Yue, Chen, Xin-Ai, Mao, Xu-Ming, Li, Yong-Quan
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204314/
https://ncbi.nlm.nih.gov/pubmed/32375781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01359-4
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