Rational construction of genome-reduced and high-efficient industrial Streptomyces chassis based on multiple comparative genomic approaches

BACKGROUND: Streptomyces chattanoogensis L10 is the industrial producer of natamycin and has been proved a highly efficient host for diverse natural products. It has an enormous potential to be developed as a versatile cell factory for production of heterologous secondary metabolites. Here we develo...

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Veröffentlicht in:Microb Cell Fact
Hauptverfasser: Bu, Qing-Ting, Yu, Pin, Wang, Jue, Li, Zi-Yue, Chen, Xin-Ai, Mao, Xu-Ming, Li, Yong-Quan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348691/
https://ncbi.nlm.nih.gov/pubmed/30691531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-019-1055-7
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