Comprehensive dissection of dispensable genomic regions in Streptomyces based on comparative analysis approach

BACKGROUND: Large-scale genome reduction has been performed to significantly improve the performance of microbial chassis. Identification of the essential or dispensable genes is pivotal for genome reduction to avoid synthetic lethality. Here, taking Streptomyces as an example, we developed a combin...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Bu, Qing-Ting, Li, Yue-Ping, Xie, Huang, Wang, Jue, Li, Zi-Yue, Chen, Xin-Ai, Mao, Xu-Ming, Li, Yong-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204314/
https://ncbi.nlm.nih.gov/pubmed/32375781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01359-4
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