Activation of anthrachamycin biosynthesis in Streptomyces chattanoogensis L10 by site-directed mutagenesis of rpoB

Genome sequencing projects revealed massive cryptic gene clusters encoding the undiscovered secondary metabolites in Streptomyces. To investigate the metabolic products of silent gene clusters in Streptomyces chattanoogensis L10 (CGMCC 2644), we used site-directed mutagenesis to generate ten mutants...

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Gepubliceerd in:J Zhejiang Univ Sci B
Hoofdauteurs: Li, Zi-yue, Bu, Qing-ting, Wang, Jue, Liu, Yu, Chen, Xin-ai, Mao, Xu-ming, Li, Yong-Quan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Zhejiang University Press 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885405/
https://ncbi.nlm.nih.gov/pubmed/31749345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B191900344
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