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Activation of anthrachamycin biosynthesis in Streptomyces chattanoogensis L10 by site-directed mutagenesis of rpoB

Genome sequencing projects revealed massive cryptic gene clusters encoding the undiscovered secondary metabolites in Streptomyces. To investigate the metabolic products of silent gene clusters in Streptomyces chattanoogensis L10 (CGMCC 2644), we used site-directed mutagenesis to generate ten mutants...

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Podrobná bibliografie
Vydáno v:J Zhejiang Univ Sci B
Hlavní autoři: Li, Zi-yue, Bu, Qing-ting, Wang, Jue, Liu, Yu, Chen, Xin-ai, Mao, Xu-ming, Li, Yong-Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: Zhejiang University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885405/
https://ncbi.nlm.nih.gov/pubmed/31749345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B191900344
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