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Activation of anthrachamycin biosynthesis in Streptomyces chattanoogensis L10 by site-directed mutagenesis of rpoB

Genome sequencing projects revealed massive cryptic gene clusters encoding the undiscovered secondary metabolites in Streptomyces. To investigate the metabolic products of silent gene clusters in Streptomyces chattanoogensis L10 (CGMCC 2644), we used site-directed mutagenesis to generate ten mutants...

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Bibliografske podrobnosti
izdano v:J Zhejiang Univ Sci B
Main Authors: Li, Zi-yue, Bu, Qing-ting, Wang, Jue, Liu, Yu, Chen, Xin-ai, Mao, Xu-ming, Li, Yong-Quan
Format: Artigo
Jezik:Inglês
Izdano: Zhejiang University Press 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885405/
https://ncbi.nlm.nih.gov/pubmed/31749345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B191900344
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