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Generalizable sgRNA design for improved CRISPR/Cas9 editing efficiency

MOTIVATION: The development of clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) technology has provided a simple yet powerful system for targeted genome editing. In recent years, this system has been widely used for various gene editing application...

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Bibliografische gegevens
Gepubliceerd in:Bioinformatics
Hoofdauteurs: Hiranniramol, Kasidet, Chen, Yuhao, Liu, Weijun, Wang, Xiaowei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203743/
https://ncbi.nlm.nih.gov/pubmed/31971562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa041
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