TSH Receptor Homodimerization in Regulation of cAMP Production in Human Thyrocytes in vitro

Thyrotropin hormone (TSH) was reported to exhibit biphasic regulation of cAMP production in human thyroid slices; specifically, upregulation at low TSH doses transitioning to inhibition at high doses. We observed this phenomenon in HEK293 cells overexpressing TSH receptors (TSHRs) but in only 25% of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Endocrinol (Lausanne)
Prif Awduron: Boutin, Alisa, Krieger, Christine C., Marcus-Samuels, Bernice, Klubo-Gwiezdzinska, Joanna, Neumann, Susanne, Gershengorn, Marvin C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Endocrinology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7203478/
https://ncbi.nlm.nih.gov/pubmed/32425890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00276
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg