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Chemical Approaches to Inhibiting the Hepatitis B Virus Ribonuclease H

Hepatitis B virus (HBV) chronically infects >250 million people and kills nearly a million annually, and current antivirals cannot clear the infection or adequately suppress disease. The virus replicates by reverse transcription, and the dominant antiviral drugs are nucleos(t)ide analogs that tar...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Tavis, John E., Zoidis, Grigoris, Meyers, Marvin J., Murelli, Ryan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202671/
https://ncbi.nlm.nih.gov/pubmed/29565562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00045
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