The Hepatitis B Virus Ribonuclease H Is Sensitive to Inhibitors of the Human Immunodeficiency Virus Ribonuclease H and Integrase Enzymes

Nucleos(t)ide analog therapy blocks DNA synthesis by the hepatitis B virus (HBV) reverse transcriptase and can control the infection, but treatment is life-long and has high costs and unpredictable long-term side effects. The profound suppression of HBV by the nucleos(t)ide analogs and their ability...

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Main Authors: Tavis, John E., Cheng, Xiaohong, Hu, Yuan, Totten, Michael, Cao, Feng, Michailidis, Eleftherios, Aurora, Rajeev, Meyers, Marvin J., Jacobsen, E. Jon, Parniak, Michael A., Sarafianos, Stefan G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551811/
https://ncbi.nlm.nih.gov/pubmed/23349632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003125
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