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Hepatitis B virus genetic diversity has minimal impact on sensitivity of the viral ribonuclease H to inhibitors
Hepatitis B virus (HBV) causes hepatitis, cirrhosis, liver failure, and liver cancer, but the current therapies that employ either nucelos(t)ide analogs or (pegylated)interferon α do not clear the infection in the large majority of patients. Inhibitors of the HBV ribonuclease H (RNaseH) that are bei...
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| Publicado no: | Antiviral Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5099120/ https://ncbi.nlm.nih.gov/pubmed/27693161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.09.009 |
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