Purification and enzymatic characterization of the hepatitis B virus ribonuclease H, a new target for antiviral inhibitors

Hepatitis B virus (HBV) reverse transcription requires coordinated function of the reverse transcriptase and ribonuclease H (RNaseH) activities of the viral polymerase protein. The reverse transcriptase has been biochemically characterized, but technical difficulties have prevented both assessment o...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antiviral Res
Auteurs principaux: Villa, Juan Antonio, Pike, Daniel P., Patel, Kunjan B., Lomonosova, Elena, Lu, Gaofeng, Abdulqader, Roz, Tavis, John E.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980287/
https://ncbi.nlm.nih.gov/pubmed/27321664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.06.005
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