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Mrx6 regulates mitochondrial DNA copy number in Saccharomyces cerevisiae by engaging the evolutionarily conserved Lon protease Pim1

Mitochondrial function depends crucially on the maintenance of multiple mitochondrial DNA (mtDNA) copies. Surprisingly, the cellular mechanisms regulating mtDNA copy number remain poorly understood. Through a systematic high-throughput approach in Saccharomyces cerevisiae, we determined mtDNA–to–nuc...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Biol Cell
Päätekijät: Göke, Aylin, Schrott, Simon, Mizrak, Arda, Belyy, Vladislav, Osman, Christof, Walter, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202074/
https://ncbi.nlm.nih.gov/pubmed/31532710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-08-0470
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