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Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease

Proteins in a natural environment are constantly challenged by stress conditions, causing their destabilization, unfolding, and, ultimately, aggregation. Protein aggregation has been associated with a wide variety of pathological conditions, especially neurodegenerative disorders, stressing the impo...

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Detalhes bibliográficos
Main Authors: Bender, Tom, Lewrenz, Ilka, Franken, Sebastian, Baitzel, Catherina, Voos, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046053/
https://ncbi.nlm.nih.gov/pubmed/21209324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0718
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