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Multicomponent Pyrazole Synthesis from Alkynes, Nitriles, and Titanium Imido Complexes via Oxidatively Induced N–N Bond Coupling

Pyrazoles are an important class of heterocycles found in a wide range of bioactive compounds and pharmaceuticals. Pyrazole synthesis often requires hydrazine or related reagents where an intact N–N bond is conservatively installed into a pyrazole precursor fragment. Herein, we report the multicompo...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Pearce, Adam J., Harkins, Robin P., Reiner, Benjamin R., Wotal, Alexander C., Dunscomb, Rachel J., Tonks, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201868/
https://ncbi.nlm.nih.gov/pubmed/32043879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b13173
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