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Azaphilic versus Carbophilic Coupling at C=N Bonds: Key Steps in Titanium‐Assisted Multicomponent Reactions

Consecutive C‐ and N‐arylation of N‐heterocyclic nitriles is mediated by titanium(IV) alkoxides. The carbo‐ and azaphilic arylation step may be separated by choosing the order in which the two equivalents of aryl transfer reagent are added. In the course of this transformation, the ancillary N‐heter...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Roth, Torsten, Wadepohl, Hubert, Clot, Eric, Gade, Lutz H.
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY‐VCH Verlag 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832833/
https://ncbi.nlm.nih.gov/pubmed/26542982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201503732
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