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Azaphilic versus Carbophilic Coupling at C=N Bonds: Key Steps in Titanium‐Assisted Multicomponent Reactions

Consecutive C‐ and N‐arylation of N‐heterocyclic nitriles is mediated by titanium(IV) alkoxides. The carbo‐ and azaphilic arylation step may be separated by choosing the order in which the two equivalents of aryl transfer reagent are added. In the course of this transformation, the ancillary N‐heter...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chemistry
Main Authors: Roth, Torsten, Wadepohl, Hubert, Clot, Eric, Gade, Lutz H.
Format: Artigo
Jezik:Inglês
Izdano: WILEY‐VCH Verlag 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832833/
https://ncbi.nlm.nih.gov/pubmed/26542982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201503732
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