Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin α(IIb)β(3) inside-out but not outside-in signals

BACKGROUND: Columbianadin (CBN) is one of the main coumarin constituents isolated from Angelica pubescens. The pharmacological value of CBN is well demonstrated, especially in the prevention of several cancers and analgesic activity. A striking therapeutic target for arterial thrombosis is inhibitio...

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Bibliografiska uppgifter
I publikationen:J Biomed Sci
Huvudupphovsmän: Hou, Shaw-Min, Hsia, Chih-Wei, Tsai, Cheng-Lin, Hsia, Chih-Hsuan, Jayakumar, Thanasekaran, Velusamy, Marappan, Sheu, Joen-Rong
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2020
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201758/
https://ncbi.nlm.nih.gov/pubmed/32375785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-0619-5
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