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Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma

The majority of high-risk neuroblastomas can be divided into three distinct molecular subgroups defined by the presence of MYCN amplification, upstream TERT rearrangements or alternative lengthening of telomeres (ALT). The common defining feature of all three subgroups is altered telomere maintenanc...

詳細記述

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書誌詳細
出版年:J Exp Clin Cancer Res
主要な著者: George, S. L., Parmar, V., Lorenzi, F., Marshall, L. V., Jamin, Y., Poon, E., Angelini, P., Chesler, L.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201617/
https://ncbi.nlm.nih.gov/pubmed/32375866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01582-2
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