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Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma

The majority of high-risk neuroblastomas can be divided into three distinct molecular subgroups defined by the presence of MYCN amplification, upstream TERT rearrangements or alternative lengthening of telomeres (ALT). The common defining feature of all three subgroups is altered telomere maintenanc...

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Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: George, S. L., Parmar, V., Lorenzi, F., Marshall, L. V., Jamin, Y., Poon, E., Angelini, P., Chesler, L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201617/
https://ncbi.nlm.nih.gov/pubmed/32375866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01582-2
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