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Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma

The majority of high-risk neuroblastomas can be divided into three distinct molecular subgroups defined by the presence of MYCN amplification, upstream TERT rearrangements or alternative lengthening of telomeres (ALT). The common defining feature of all three subgroups is altered telomere maintenanc...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: George, S. L., Parmar, V., Lorenzi, F., Marshall, L. V., Jamin, Y., Poon, E., Angelini, P., Chesler, L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201617/
https://ncbi.nlm.nih.gov/pubmed/32375866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01582-2
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