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Novel therapeutic strategies targeting telomere maintenance mechanisms in high-risk neuroblastoma

The majority of high-risk neuroblastomas can be divided into three distinct molecular subgroups defined by the presence of MYCN amplification, upstream TERT rearrangements or alternative lengthening of telomeres (ALT). The common defining feature of all three subgroups is altered telomere maintenanc...

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Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: George, S. L., Parmar, V., Lorenzi, F., Marshall, L. V., Jamin, Y., Poon, E., Angelini, P., Chesler, L.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201617/
https://ncbi.nlm.nih.gov/pubmed/32375866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01582-2
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