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Safety and Immunogenicity of the Respiratory Syncytial Virus Vaccine RSV/ΔNS2/Δ1313/I1314L in RSV-Seronegative Children

BACKGROUND: Respiratory syncytial virus (RSV) is the leading global cause of severe pediatric acute respiratory tract illness, and a vaccine is needed. RSV/ΔNS2/Δ1313/I1314L contains 2 attenuating elements: (1) deletion of the interferon antagonist NS2 gene and (2) deletion of codon 1313 of the RSV...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Karron, Ruth A, Luongo, Cindy, Mateo, Jocelyn San, Wanionek, Kimberli, Collins, Peter L, Buchholz, Ursula J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199783/
https://ncbi.nlm.nih.gov/pubmed/31605113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz408
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