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Protective role of p53 in doxorubicin-induced cardiomyopathy as a mitochondrial disease
Doxorubicin is widely used against cancer but carries the risk of a progressive cardiomyopathy associated with mitochondrial loss. Using genetic models, our recent study demonstrates that mitochondrial genomic DNA regulation by tumor protein p53 (TP53, best known as p53) prevents the cardiotoxicity...
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| Udgivet i: | Mol Cell Oncol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7199752/ https://ncbi.nlm.nih.gov/pubmed/32391420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1724598 |
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