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Dietary nitrate supplementation protects against doxorubicin-induced cardiomyopathy by improving mitochondrial function

OBJECTIVES: We tested the hypothesis that chronic dietary nitrate supplementation protects against doxorubicin-induced cardiomyopathy through improving ventricular function and reducing mitochondrial respiratory chain damage. BACKGROUND: Doxorubicin is a powerful anthracycline antibiotic used to tre...

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Detalhes bibliográficos
Main Authors: Zhu, Shu-Guang, Kukreja, Rakesh C., Das, Anindita, Chen, Qun, Lesnefsky, Edward J., Xi, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127335/
https://ncbi.nlm.nih.gov/pubmed/21596234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2011.01.024
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