Dietary Inorganic Nitrate Alleviates Doxorubicin Cardiotoxicity: Mechanisms and Implications

Doxorubicin (DOX) is one of the most powerful and widely prescribed chemotherapeutic agents to treat divergent human cancers. However, the clinical use of DOX is restricted due to its severe cardiotoxic side-effects. There has been ongoing search for cardioprotectants against DOX toxicity. Inorganic...

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Main Authors: Xi, Lei, Zhu, Shu-Guang, Das, Anindita, Chen, Qun, Durrant, David, Hobbs, Daniel C., Lesnefsky, Edward J., Kukreja, Rakesh C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360792/
https://ncbi.nlm.nih.gov/pubmed/22484629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2012.03.006
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