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Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis

Doxorubicin (DOX) is a widely used, potent chemotherapeutic agent; however, its clinical application is limited because of its dose-dependent cardiotoxicity. DOX’s cardiotoxicity involves increased oxidative/nitrative stress, impaired mitochondrial function in cardiomyocytes/endothelial cells and ce...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Hao, Enkui, Mukhopadhyay, Partha, Cao, Zongxian, Erdélyi, Katalin, Holovac, Eileen, Liaudet, Lucas, Lee, Wen-Shin, Haskó, György, Mechoulam, Raphael, Pacher, Pál
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461586/
https://ncbi.nlm.nih.gov/pubmed/25569804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00261
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