Caricamento...
PBRM1 suppresses tumor growth as a novel p53 acetylation reader
The reader(s) for acetylated tumor antigen p53 remains elusive. Here, PBRM1 (polybromo-1) is identified as a reader for acetylated lysine382 on p53 through its bromodomain 4 (BD4). PBRM1 BD4 mutants fail to support p53 transcriptional activity and suppress tumor growth. Thus PBRM1 suppresses tumor g...
Salvato in:
| Pubblicato in: | Mol Cell Oncol |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7199739/ https://ncbi.nlm.nih.gov/pubmed/32391422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1729680 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|